Does O3 raise cholesterol?

On the contrary, the omega-3 fatty acids found in fish and calamari oil are very effective for supporting healthy triglyceride levels and non-HDL cholesterol (both are bad lipids), as well as promoting healthy cholesterol levels, HDL. Omega-3s have also been found to be effective in combination with red yeast rice, which also supports healthy cholesterol levels. 
 
The evidence for the cardiovascular benefits of omega-3s is so strong that organizations such as the American Heart Association and the European Society of Cardiology have made public recommendations for increased intake of omega-3 for heart health.